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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK2A1 All Species: 14.85
Human Site: S356 Identified Species: 20.42
UniProt: P68400 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P68400 NP_001886.1 391 45144 S356 A N M M S G I S S V P T P S P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112211 397 46613 R356 A N M M S E M R F Y H V A Q A
Dog Lupus familis XP_534375 403 46681 F356 A N M M S G Q F Y F S I L R E
Cat Felis silvestris
Mouse Mus musculus Q60737 391 45143 S356 A N M M S G I S S V P S P S P
Rat Rattus norvegicus P19139 391 45055 S356 A N M M S G I S S V P T P S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507666 350 41142 V329 H P Y F Y P V V K E Q S Q P S
Chicken Gallus gallus P21868 391 45172 S356 A S M M S G I S S V P T P S P
Frog Xenopus laevis P28020 392 45169 I356 S A S M M S G I S T V P T P S
Zebra Danio Brachydanio rerio NP_001002164 393 45422 G356 T S S M I T G G V T S L S S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08181 336 39941 E315 V D R L T A R E A M A H P Y F
Honey Bee Apis mellifera XP_393260 350 41645 P324 M E H P Y F Y P I V K D Q G R
Nematode Worm Caenorhab. elegans P18334 360 42239 Q338 A R A N G T E Q A D G Q G A S
Sea Urchin Strong. purpuratus XP_785475 398 46271 S354 A T N S S S A S S T R K A I D
Poplar Tree Populus trichocarpa
Maize Zea mays P28523 332 39212 L311 H Q E R L T A L E A M T H P Y
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08467 333 39240 E312 Q D R L T A K E A M A H A Y F
Baker's Yeast Sacchar. cerevisiae P19454 339 39385 D318 I D N L L R Y D H Q E R L T A
Red Bread Mold Neurospora crassa Q8TG13 336 39621 P315 A K E A M A H P Y F A P V R D
Conservation
Percent
Protein Identity: 100 N.A. 90.4 97 N.A. 97.4 98.4 N.A. 75.4 97.9 94.9 89 N.A. 75.9 79.5 72.8 78.3
Protein Similarity: 100 N.A. 92.1 97 N.A. 98.7 98.9 N.A. 82.6 98.9 97.1 93.8 N.A. 81.8 86.1 82.3 87.1
P-Site Identity: 100 N.A. 33.3 40 N.A. 93.3 100 N.A. 0 93.3 13.3 13.3 N.A. 6.6 6.6 6.6 26.6
P-Site Similarity: 100 N.A. 40 40 N.A. 100 100 N.A. 13.3 100 20 20 N.A. 40 6.6 20 26.6
Percent
Protein Identity: N.A. 65.2 N.A. 63.4 49.8 61.1
Protein Similarity: N.A. 74.9 N.A. 75.4 63.6 72.8
P-Site Identity: N.A. 6.6 N.A. 0 0 6.6
P-Site Similarity: N.A. 6.6 N.A. 33.3 20 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 53 6 6 6 0 18 12 0 18 6 18 0 18 6 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 18 0 0 0 0 0 6 0 6 0 6 0 0 12 % D
% Glu: 0 6 12 0 0 6 6 12 6 6 6 0 0 0 6 % E
% Phe: 0 0 0 6 0 6 0 6 6 12 0 0 0 0 12 % F
% Gly: 0 0 0 0 6 30 12 6 0 0 6 0 6 6 0 % G
% His: 12 0 6 0 0 0 6 0 6 0 6 12 6 0 0 % H
% Ile: 6 0 0 0 6 0 24 6 6 0 0 6 0 6 0 % I
% Lys: 0 6 0 0 0 0 6 0 6 0 6 6 0 0 0 % K
% Leu: 0 0 0 18 12 0 0 6 0 0 0 6 12 0 0 % L
% Met: 6 0 36 48 12 0 6 0 0 12 6 0 0 0 0 % M
% Asn: 0 30 12 6 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 6 0 6 0 6 0 12 0 0 24 12 30 18 24 % P
% Gln: 6 6 0 0 0 0 6 6 0 6 6 6 12 6 0 % Q
% Arg: 0 6 12 6 0 6 6 6 0 0 6 6 0 12 6 % R
% Ser: 6 12 12 6 42 12 0 30 36 0 12 12 6 30 24 % S
% Thr: 6 6 0 0 12 18 0 0 0 18 0 24 6 6 0 % T
% Val: 6 0 0 0 0 0 6 6 6 30 6 6 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 12 0 12 0 12 6 0 0 0 12 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _